Error message

  • Deprecated function: Function create_function() is deprecated in include_once() (line 1 of /home4/vibu/public_html/journalijcrls.com/sites/default/settings.php).
  • Deprecated function: implode(): Passing glue string after array is deprecated. Swap the parameters in drupal_get_feeds() (line 394 of /home4/vibu/public_html/journalijcrls.com/includes/common.inc).
  • Deprecated function: The each() function is deprecated. This message will be suppressed on further calls in _menu_load_objects() (line 569 of /home4/vibu/public_html/journalijcrls.com/includes/menu.inc).

A comprehensive review on phytosomal drug delivery system

Author: 
Swathi, R., Joshna Rani, S. and Hari Kishore, A.
Abstract: 

Medicinal herbs are potential source of therapeutics and they have attained a prominent role in health care system all over the world. Phytoconstituents, despite having excellent bioactivity In-vitro demonstrate less or no In- vivo actions due to their poor lipid solubility, improper molecular sizes and cannot absorb by passive diffusion. Phytosome, which is a novel emerging technique in herbal drug technology removes the limitations of the traditional drug delivery systems and enhances the bioavailability of herbal extracts. So, Phytosomes exhibit better pharmacokinetic and pharmacodynamic profile than conventional herbal extracts. This Phytosome technology can be utilized in pharmaceutical industries to solve the bioavailability related problems for various herbal formulations and provides better and effective treatment in various diseases like diabetes, hepatic toxicity and ageing etc. The recent trend is to improve the therapeutic performance of the conventional herbal drugs by formulating them as a new drug delivery system rather than going for costly research for a new entity.

Download PDF: