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Pregnancy outcome in gestational diabetes mellitus under treatment and its correlation with hba1c at 36 weeks

Author: 
Dr. Jothi Sundaram, Dr. Shanthi. C. and Dr. Kayal
Abstract: 

Brain Objectives: To observe pregnancy outcomes in gestational diabetes mellitus (GDM) under treatment. Methods: Pregnant mothers diagnosed with GDM (N=40) age: 27.44±7.91yr; body mass index, BMI: 26.88±4.16 kg/m2; mean±SD) on the basis of WHO 2013 criteria were compared for pregnancy outcome irrespective of gestational age. HbA1c was measured in all mothers. Gestational hypertension, preeclampsia, premature rupture of membrane (PROM), hydramnios, recurrent urinary tract infection (UTI), recurrent moniliasis, intrauterine growth retardation (IUGR), intra uterine death (IUD), mode of delivery, birth weight, birth injury, neonatal hypoglycemia, hyperbilirubinemia, respiratory distress syndrome (RDS), congenital anomaly were recorded at every trimester.40 mothers(GDM on MNT =9, GDM first started on MNT then converted to Insulin treatment =13, GDM on Insulin=18) could be followed for outcomes to the end of pregnancy. All the GDM mothers were offered standard treatment throughout pregnancy period. Results: HbA1c monitoring (less than or equal to 5.7% in 15; 5.7% to 7% in 20; 7.1% - 8% in 2; more than 8% in 3).Outcome events in GDM with associated co-morbidity: preeclampsia- 7 ; Hypothyroid – 5; Long period infertility – 7; Anemia – 3; PCOS-6; Recurrent GDM -1; PROM-7; hydramnios-4; recurrent UTI-8; recurrent moniliasis- 2; Labour Naturalis- 7; Instrumental Delivery -2; Caesarean section- 31; small for gestational age (SGA)-7; large for gestational age (LGA)- 6; IUGR- 2; neonatal hypoglycemia-2; hyperbilirubinemia-1; RDS- 1 and birth injury-0, congenital anomaly-2,Preterm delivery- 6 ; caesarean section-31, Perinatal mortality - 1 Conclusions: With proper treatment and good Glycemic Control adverse events on fetal outcome are relatively less in GDM.

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