This study is designed to find out the relationship between female participation to the labor force, internal and external factors that limiting to their labor force participation and negative aspects of working for female. This research was carried out with 900 women between the ages of 15-64, living in Eskişehir. The data was collected through “Perception Scale on determinants of Female Participation to the Labor Force” developed by researchers. These data were analyzed with Second Order Confirmatory Factor Analysis by using the statistical package LISREL. The findings from the study revealed that the scale was valid and reliable and that internal factors and external factors that limiting to their labor force participation and negative aspects of working for female affect directly female participation to the labor force.