The antioxidant potency of methanol extracts of Ampelocissus araneosa leaf, stem and root was investigated. Total antioxidant activity was determined using Free radical scavenging activity (DPPH) and Ferrous ion chelating activity. In addition, the content of phenols and total flavonoids were measured in the extracts. The free radical scavenging capacity and ferrous ion chelation activity were found to be increasing with increase in extract concentration from 50 to 250 g/ml and 1000 to 5000 g/ml respectively. The result showed that the root extract has higher antioxidant activity than stem and leaf extract. GC-MS profile of these extracts were investigated to find out the possible phytochemical involved in antioxidant activity.
