Despite clinical advances in anticancer therapy, there is still a need for novel anticancer metabolites, with higher efficacy and lesser side effects. The present study evaluated the anticancer, angiogenic activity, phytochemical compounds, and antimicrobial activity of the plant Cansjera rheedii J.Gmelin. Cansjerarheedhii (opiliaceae) is a climbing shrub, Whole plant of Cansjerarheedhii was used by the tribes of Auroville village near Puducherry for various liver disorders. For checking the cytotoxicity, trypan blue assay result shows the presence of active compounds in the ethanolic plant extract. This is confirmed by MTT assay which gives an IC50 value of 150μg/ml on MCF-7 and 150μg/ml on HT-29 cell lines. The phytochemical study of ethanolic extract of Cansjera rheedii showed the presence of alkaloids, carbohydrates, flavonoids, phenols, saponins, amino acids, terpanoids and tannin. Ethanolic plant extract shows more active in antimicrobial and angiogenicactivity.Future studies are necessary for chemical characterization of the active principles and more extensive biological evaluation.
