Pesticides are number of chemicals used in intensive vegetable farming to control pathogen, pest and weed. Further, pesticides play a significant role by keeping many dreadful diseases. However, their use with high frequency may be an environmental problems. This study disingned insecticide residues (Organochlorine, Organophosphorus and Pyrethri-noid) in vegetable farms soil of Cotonou and Seme-kpodji area (Southen of Benin). Twenty soil samples from four vegetable farms were collected. Multiclass residues extraction was performed using soxhlet with solvent system hexane : acetone 3:2 (v/v). Residue analysis was performed using a GC-MS in SIS mode. MedCalc Statistical Software version 15.0. was used for the statistical analysis. The results revealed that most of the samples are contaminated by Organo-chlorine Organophosphorus and Pyrethroid residues. Among Organochlorine residues analyzed, 60 % of dieldrin, 35% of DDT, 65% of DDE, 75% of endosulfan II and 70% of endosufan II were detected. For Pyrethroid residues 25% of cypermethrin, 40% of cyfluthrin, 50% of fenpropathin and 95% of lambda cyhalothin were found in the soil samples. For Organophosphorus analyzed, 55% of profenofos 55% of chlorpyrifos and 30% of parathion were quantified. Levels of pesticide residues found in vegetable farms soils may be consider like an environmental problem.