Novel 1-(4-substitutedphenyl)-3-(4-substitutedphenyl) substituted benzaldehyde with several acetophenone derivatives. Subsequently, the cyclocondensation hydrazine gives5-(4-substitutedphenyl)-3- the ability as antibacterial and antifungal activity. albicans, Aspergillus niger are inhibit by the action on synthesized compounds -prop-2-en-1-oneswere synthesized from a Claisen (4-substituted phenyl)-1H-pyrazole derivatives. Several of these compounds were screened for Growth of S. aureus (gram positive), E.Coli (gram negative) bacteria and -Schmidt reaction of4- reaction of chalcones with Candida
