The results of the repellent activity of C. gigantea at three different extracts (methanol, ethanol and acetone) and three different concentration of 1.0, 2.5 and 5.0 mg/cm2 were applied on skin of fore arm in man and exposed against 3 to 4 days old unfed adult female Ae. aegypti mosquito. In this observation the C. gigantea extract gave protection against mosquito bites without showing any allergic to the test person and also the repellent activity dependent on the strength of the lowest concentration extract of 1.0 mg/cm2 against Ae.aegypti for the exposure period of 2.0 hours and 30 minutes.