Heliotropium indicum, a herbaceous medicinal plant belonging to the family Boranginaceae, used in Siddha system of medicine to cure inflammation, ulcers, wounds, all types of fevers, particularly used in scorpion sting to reduce the inflammation and pain. The present study deals with its analgesic and antipyretic activity in rat models. Aqueous and chloroform extracts of the herb Heliotropium indicum were prepared and analyzed for its pharmacological activity. Albino rats of either sex are used for analgesic and antipyretic property of the extract by using hot plate method and brewer’s yeast induced pyrexia method. Analgesic activity showed significant effect even at a minimal dose over the standard drug. The antipyretic activity revealed that the extracts showed an effective result at 75mg/kg dosage. The findings in the study suggest that the aqueous and chloroform extract of the herb Heliotropium indicum possesses analgesic and anti-inflammatory activities. These results may prove the fact that the herb may be used as analgesic and anti-inflammatory along with its adaptogenic properties.
