Background: Dental caries is one of the most leading cause of oral diseases among the globe, numerous dentifrices and mouthwashes come to the market for the remedy. Thus, more research are focussed on natural system of medicine like Ayurveda and its use for curbing oral health problems. Aim and Objectives: To assess the antimicrobial activity of commercially available five dentifrices against streptococcus mutans. Materials and method: For the present study we used strains of micro-organisms- Streptococcus mutants Strain- 890 from MTCC. To revive the strains Brain Heart Infusion Agar (BHI agar media) was used. Double blinding was done and samples were coded with alphabets to avoid examiner bias. The plates were kept in incubation chamber for 24 hours. After 24 hours, 48 hours, 72 hours The zone of inhibition was measured with the help of Hi Antibiotic Zone scale from HiMedia Laboratories Limited, Mumbai. Observations and Results: After assessing the antimicrobial activity for 24 H, 48 H and 72 H, DantKanti was found to be most effective with the highest zone of inhibition 28.16±0.75, followed by Meswak. Whereas, Dabur lal and Himalaya had the least effect when compared to their counterparts. Conclusion: The result of the current study demonstrated that Dantikanti has the maximum antimicrobial effect against S.mutans followed by Meswak and Babol, remaining dentifrices like Himalaya and Dabur lal had the least effect against the microbes. Thus, when compared with all other commercially available ayurvedic dentifrices Dantikanti proved to be more effective at 24 hours, 48 hours and 72 hours among all others.
