The interest of this paper is to show that corruption and institutional quality through human capital were among the main key failure factors for the development of the nations of the MENA region and therefore when we speak of "corruption."Indeed, institutional quality through the human direct and indirect influences on economic growth in capital. Our empirical attempt, dynamic panel data (GMM) and during the period 1998 to 2006, trying to clarify the direct and indirect effects of corruption and institutional quality through human capital on economic growth in all parts comparing the results obtained in the MENA region with other regions. Our sample consists of one hundred countries on which we test the impact of institutional quality through human capital and corruption on economic growth.