In the present study an attempt was made to investigate the reproductive disturbance of the medicinal plant Ziziphus jujube leaves extract on edible fresh water fish Oreochromis mossambicus (Tilapia mossambica). Since, immemorial time the Ziziphus jujube commonly used various ways in human beings. The a adult fresh water fish were treated with the leaves extract of Ziziphus jujube 100mg/lit of water for a period of 15 days. At end of the experiment, the animals were sacrificed and dissected out the ovaries for his to pathological observation. The histopathology of ovary reveals that there were no changes in the structure of oogonia, yolk and tunica albugenea of control animals, but in 10% and 30% treated animal’s ovaries shown a remarkable changes in the structure of oogonia, the content of yolk substance, structure of oocyte wall, arrangement of columnar cells and tunica albugenea. Therefore, it concludes that the aqueous extract of Ziziphus jujube has considerable impact on the reproductive organ of fresh water fish Oreochromis mossambicus.
