Efficacy of three marine yeasts (Debaryomyceshansenii S8, Debaryomyceshansenii S100 and Candida tropicalis S186) as feed supplement for Fenneropenaeusindicus was estimated in comparison with Saccharomyces cerevisiae MTCC 36, a commercial feed and a control feed were used for the study. Biomass of yeast strains was prepared using Malt extract agar and incorporated into a standard diet to prepare yeast diets of varying concentrations. F.indicuswere fed these diets for a period of 28 days and various growth parameters such as production, FCR, SGR, GGE, RGR, PER, CUD were performed. Among the three marine yeast diets Debaryomyceshansenii S8 supported the best biogrowth parameters. Commercial feed was found to be better in efficiency compared to the Bakers yeast diet and control diet. Present study showed that the three marine yeasts used in the study could very well be used as feed supplement in aquaculture.