The aim of the study was to investigate the relationship between sprinting performance with agility and explosive power of male university handball players. Twenty seven (27) male university handball players were selected from Department of Physical Education and Sports Sciences, Annamalai University, who voluntarily participated in this study. Sprinting performance was measured by 30 meter dash, agility through T - test and explosive power through vertical jump test was selected. The result of the present study showed that product moment correlation analysis showed significant correlation between sprinting performance with agility (r = 0.580, p = 0.002) and explosive power (r = -0.491, p = 0.009). The findings of the present study indicated significant positive correlation of sprinting performance with agility and negative correlation with explosive power among male handball players. This clearly shows that players with good 30 meters sprinting performance will have better agility and explosive power.