Industrialization and westernization have influenced the life style including food habit and preferences of Indian population and this in turn resulted in dangerous health hazards such as pancreatic ductal adenocarcinoma (PDAC). ADAM8 is validated as a target for pancreatic ductal adenocarcinoma therapy. The HTVS of Zinc database obtained five prospective ligand molecules. Five molecules significantly satisfied the pharmacokinetic factors that are defined for human use and qualified as potential drug like molecules. The study concludes that five molecules could be successful molecules to be tested in invitro and invivo settings.
