The plants of the genus Phyllanthus (Euphorbiaceae) have been used as traditional medicinal materials for a long time in China, India, Brazil, and the Southeast Asian countries. They can be used for the treatment of digestive disease, jaundice, and renal calculus antimicrobial, antioxidant, anticancer, antiinflammatory, antiplasmodial, antiviral, diuretic and hepatoprotective. Particularly, Phyllanthus niruriis found throughout the tropical and subtropical regions of both hemispheres showing an impressive list of medicinal uses in many countries around the world. In this review, we highlight the properties of the specie about ethnobotanical, phytochemical, pharmacological, biological and toxicological activities as it has been described in the scientific journals of the last 10 years. The emphasis is centered to liver disorders and kidney stones, different ways of drug formulations, dosage and the precaution uses.
