Aim: The aim of this study was to identify the differences in risk factors between early and late onset pre-eclampsia. Materials and Methods: A case–control stud y was carried out involving pregnancies with pre-eclampsia and 449 controls at Gujarat Adani institute of medical science, Bhuj, Kutch, Gujarat from August 2011 to May 2014. The data were reviewed from antenatal and delivery records. Results: Factors which were significantly associated with increased risk for both early and late onset preeclampsia were family history of diabetes mellitus, high pre-pregnancy body mass index ≥ 25 kg/m2 and weight gain ≥ 0.5 kg per week. History of chronic hypertension was significantly associated with increased risk for only early onset pre-eclampsia, while family history of chronic hypertension was significantly associated with increased risk for only late onset pre-eclampsia. Conclusions: The risk factors that differ between early and late onset of pre-eclampsia were history of chronic hypertension and family history of chronic hypertension. Family history of diabetes mellitus, pre-pregnancy body mass index ≥ 25 kg/m2 and weight gain≥ 0.5 kg per week were risk factors of both early and late onset pre-eclampsia.
