The health care delivery system at tertiary level has sophisticated and modernized equipment to meet the child’s need and attain quality care. The investigator during her clinical experience observed that children were very anxious and had poor coping ability to overcome. Keeping this in view the investigator aimed to effectiveness of preoperative orientation program on psycho physiological parameters among children subjected to elective surgery. 60 children subjected to elective surgery for the first time were randomly selected, 30 children of study group received preoperative orientation to the operation theater and preoperative care prior to the surgery and 30 children of the control group received only the routine preoperative orientation prior to the surgery. The findings of the study depicted an evidence of significant difference between pretest and posttest values of all physiological measures. For the study group hence current study supported the fact that preoperative orientation program had an impact on psycho physiological parameters significant at p<0.001.