A five coordinated Trigonal bipyramidal copper (II) complex formulated as [Cu(L) NClBrS(H2O)] (1) (HL= 4-Bromo-2-[(2-thiophen-2-yl-ethylimino)-methyl]-phenol (BEP)) was synthesized and characterized by elemental, physico-chemical and spectroscopic methods. The interactions of copper (II) complex towards bovine serum albumin (BSA) were examined with the help of absorption and fluorescence spectroscopic tools. The ligand and copper complex-1 has been screened for antimicrobial activity by agar disk diffusion against two Gram‐positive bacteria and one Gram‐negative bacterium. The compound showed good antibacterial activity when compared with known antibiotic chloramphenicol.
