Background and Objective: Here we are planning to study the toxicity of the ethanolic extract of M.concanensis leaves and synthesized silver nanoparticles from the aqueous extract of M.concanensis leaves by using wister albino rats. Material and Methods: The green route method was employed to synthesize the silver nanoparticles from aqueous extract of M.concanensis leaves. The toxicity study of M.concanensis leaves was studied by observing the changes on hematological measurements such as hemoglobin, PCV, WBC, RBC and Platelets. Results: Among all the tested extracts of M.concanensis Nimmo leaves, chloroform, ethyl acetate and aqueous extracts has the lowest number of phytochemicals. The ethanolic extract of the leaves was found rich source of phytochemicals as compared to the other extracts. The aqueous extract of Moringa concanensis Nimmo leaves revealed that it has a very good source of silver nanoparticles. Based on the study the 200mg of ethanlic extract and 150µg of silver nanoparticles was selected as an optimum dose. Conclusion: Based on the above findings, it was concluded as this research work may gives a clear understand on the toxicity of ethanolic extract and silver nanoparticles from the leaves of Moringa concanensis Nimmo. This results may used in the further research in this plant.
