A 80-year-old male patient with a clinical picture of macroscopic hematuria, subsequent contact with the family of the Saturniidae family, on admission is documented by prolonged coagulation times, consumption of fibrinogen and elevation of azotees. It was managed with antilonomic serum and is a problem of reaction and allergic reaction required management with corticosteroids, plasma transfusion and tranexamic acid. In this case report, a review of the literature on poison literature, pathophysiology and treatment measures is carried out.