Nutrient contents found in the diet have a significant influence on health benefits of an organism. Nowadays a number of synthetic energy drinks are in use; however the quality and quantity of nutrients found in these synthetic energy drinks are different. Present study has been undertaken in Drosophila melanogaster (D. melanogaster) to evaluate the effect of synthetic energy (Burn) on male mating ability and progeny production. It was noticed that larvae of D. melanogaster has shown increased rate of feeding in natural energy drinks compared to wheat cream agar medium and synthetic energy drinks. Males fed with natural energy drinks had inseminated significantly greater number of females in a given unit time and produced significantly greater number of progeny than those males fed with synthetic energy drinks. Thus this study suggests that synthetic energy drinks reduces male fitness in D. melanogaster.